-
CoreXymide, a unique ingredient, suppresses two
major enzymes, promoting barrier functions,
moisturization, and wrinkle reduction.
Three benefits of CoreXymide※1
Simultaneously suppressing two enzymes
that damage the basement membrane.
CoreXymide suppresses the activity of heparanase in three hours
CoreXymide suppresses the activity of MMP-9 in 30 minutes
Shiseido identified two major enzymes, heparanase and MMP-9, that damage the basement membrane, and developed CoreXymide, a unique, highly functional ingredient, from more than 20,000 potential substances.
CoreXymide suppresses the activity of heparanase in three hours and MMP-9 in 30 minutes.
-
A mechanism that works on the basement membrane to provide multiple benefits for the entire skin.
CoreXymide works on the basement membrane, bringing positive impact on both the epidermis and dermis through the epidermal stem cells. When the basement membrane is maintained in a healthy condition, the ability to nurture epidermal stem cells is also maintained, and epidermal stem cells are properly differentiated to produce epidermal cells, which can improve barrier function and skin moisture level. Furthermore, improved condition of epidermal cells positively impacts the dermis, and works on the fibroblasts to promote the production of collagen, which can lead to a reduction in wrinkles.
Research Information Based on CoreXymide
When, starting from the basement membrane, the decrease in epidermal stem cells is kept low…
The renewal of epidermal cell is promoted.
*Effects of CoreXymide applied on human skin
When, starting from the basement membrane, the production of epidermal hyaluronic acid is promoted…
The skin moisture level and water content in the stratum corneum tend to increase.
*Effects of CoreXymide applied on human skin
When, starting from the basement
membrane, the production of filaggrin is
promoted…
Improvement in the skin barrier function can be expected.
*Effects of CoreXymide applied on human skin
When, starting from the basement
membrane, the production of collagen is
promoted, a reduction in wrinkles can be
expected.
